Z-Tag is a novel and versatile protein purification technology developed by Nucleics that provides a number of superior properties over currently available protein purification systems. The Z-Tag™ system employs a novel protein fusion technology to link the target protein of choice to a specific protein tag. The protein tag’s key property is its ability to undergo reversible self-polymerisation induced by defined and controllable physical/ chemical conditions. The Z-Tag™ system is matrix-independent and thus avoids problems encountered during industrial scale-up associated with column and absorption bed usage.
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