A common problem with Sanger DNA sequencing is a rapid falloff in peak signal strength - what is known colloquially as a “ski-slope” trace. This problem can often be difficult to…
- 1 Dec 2015In Depth: Extra Normalization
- 30 Nov 2015In Depth: Automatic Bubble Spike Removal
One production problem that can occur with Sanger DNA sequencing is sharp spikes in the raw data channel. These spikes can appear anywhere in the raw channel, are…
- 27 Nov 2015PeakTrace 6.12 Linux x86_64 Released
We have released PeakTrace 6.12 for x86_64 Redhat/CentOS 6. This fixes a few minor bugs, but it does include one important improvement - bubble spike correction. Bubble spikes are sharp spikes…
- 24 Nov 2015In Depth: Clean Baseline
The clean baseline setting within the PeakTrace Basecaller™ is a cosmetic option that can be used to improve the appearance of trace files. While in an ideal world…
- 20 Nov 2015Why is the default Good Base Improvement −20?
A question we occasionally get asked is why is the default good base improvement set to −20? The reasons are complex, but it is basically due to the way…
- 13 Nov 2015Automatic updates of Auto PeakTrace 6
We have updated the automatic update system so that it now supports Auto PeakTrace 6 updates. This means if you are running Auto PeakTrace 6 then it will…
- 12 Nov 2015Auto PeakTrace 6.11 Released
We have released Auto PeakTrace 6.11. This is just a small bug update release to fix an interaction issue with mixed basecalling and trace trimming. It is recommended…
- 11 Nov 2015PeakTrace 6.11 Linux x86_64 Released
We have released PeakTrace 6.11 for x86_64 Redhat/CentOS 6. This update has many improvements and enhancements over previous versions and is a recommended update for all users of…
- 9 Nov 2015Auto PeakTrace 6.10 Released
We have released the latest version of Auto PeakTrace - 6.10. This update is a major release incorporating a large number of improvements and enhancements. The list of…
- 8 Nov 2015What settings are used with the free version of PeakTrace?
A question we get asked occasionally is what PeakTrace Basecaller settings are used with the free PeakTrace Online version? Because the online version is intended to support the widest…